HomeNanotechnologyA microfluidic method for synthesis and kinetic profiling of branched gold nanostructures

A microfluidic method for synthesis and kinetic profiling of branched gold nanostructures


Automatized approaches for nanoparticle synthesis and characterization symbolize an important asset to their applicability within the biomedical discipline by bettering reproducibility and standardization, which assist to fulfill the choice standards of regulatory authorities. The scaled-up manufacturing of nanoparticles with fastidiously outlined traits, together with intrinsic morphological options, and minimal intra-batch, batch-to-batch, and operator variability, is an pressing requirement to raise nanotechnology in direction of extra trustable organic and technological functions. On this work, microfluidic approaches have been employed to realize quick mixing and good reproducibility in synthesizing a wide range of gold nanostructures. The microfluidic setup allowed exploiting spatial decision to research the expansion evolution of the advanced nanoarchitectures. By bodily isolating intermediate response fractions, we carried out a sophisticated characterization of the form properties throughout their progress, not attainable with routine characterization strategies. Using an in-house developed methodology to assign a particular identification to shapes, we adopted the particle progress/deformation course of and recognized key response parameters for extra exact management of the generated morphologies. Apart from, this investigation led to the optimization of a one-pot multi-size and multi-shape synthesis of a wide range of gold nanoparticles. In abstract, we describe an optimized platform for extremely managed synthesis and a novel method for the mechanistic examine of shape-evolving nanomaterials.

Graphical abstract: A microfluidic approach for synthesis and kinetic profiling of branched gold nanostructures

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